Cystinuria is caused by an adjectives proximal tubular defect surrounded by which resorption of certain amino acids fail. This syndrome will increase the excretion of cysteine and other amino acids into the urine. Of the amino acids, cysteine is relatively insoluble in bitter urine, resulting in urolith formation.
Cystine kidney stones are relatively uncommon compared to other types of kidney stones because they are caused by a exceptional and inheritable disease called cystinuria. Another noteworthy distinction is that they occur within children and younger adults whereas most others in elder people
Amino acids are glibly filtered by the kidneys into the urine but average kidneys are able to reabsorb them from the urine and return them to the blood. In cystinuria, in that is a gene mutation or defect that decrease the kidney’s ability to reabsorb the cystine amino sharp from the urine. Cystine dissolves poorly in urine and form crystals that can grow into stones.
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