Give me your own answer or from a clinical textbook. No wikipedia or weblinks. I'm a med student. Don't insult me.Why are anticonvulsants Sodium Valproate, Carbamazepine, and Lamotrigine used to treat Bipolar Disorder?
I hope you appreciate any attempt at an answer you receive rather than anyone "insulted" by someone trying to help. As a med student, you should realize by very soon there's much more we don't know about prescription than we do know. For example, although we have found lithium habitually to be an excellent treatment for bipolar as well, we hold very little information in the region of its actual method of action. Even if you receive one answer in a minute, it may be disproven within even a few years. Furthermore, if you're truly looking for correctness you can't rely on books either, as their content potentially is only just as unreliable as the web, lone in an elder format. Usually only articles from peer-reviewed journal (often available as "weblinks") can be considered to be reliable. Nevertheless, my attempt at an answer:
Seizures are caused by a cataract of overstimulation in the brain as increasing amounts of excitatory neurotransmitters are released. Antiepileptics work by blocking the repeated release of these neurotransmitters, especially glutamate. This can be skilful by several mechanisms, including limiting the number of sodium channel on a membrance that can open, thereby reducing the frequency at which the neuron can stabilize and verbs firing. This same effect is useful for treating bipolar disorder, especially the hyperactivity of the passion aspect, and can also serve as a sort of buffer to keep the neuron firing at a moderate rate at adjectives times, with the postsynaptic neuron developing tolerance and increased receptor sensitivity.
Thursday, September 23, 2010
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